Southern Blotting Plays an Important Role in Various Healthcare Industry Verticals
Southern blotting is a laboratory technique used in molecular biology to detect specific DNA sequence in a blood/tissue sample. This technique was first reported in 1975 by E.N. Southern and is based on the hybridization, a process whereby a single stranded DNA is converted into a double stranded DNA by combining it with a single stranded target DNA. Southern blotting mixes the single transfer of purified DNA molecules onto a purified filter membrane and then subsequent hybridization with a restriction enzyme. This method can be used to detect DNA abnormalities or sequence variations that are specific to the region of interest. Southern blotting has gained significant momentum over the years and has played a wide role in various healthcare industry verticals, in clinical trials and diagnostic purposes. The technique also helps in detecting some chronic diseases, cancer and genetic diseases, prevalent around the world. For instance, chronic diseases such as ca...