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Development of Drugs That Aid To Regain Lost Nutritional Benefit from Food Digestion to Enhance Treatment of Short Bowel Syndrome

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  Short bowel syndrome is a complex disease that affects people who have had a lot of their small intestine removed. The group of problems is characterized by the inability of body to absorb enough nutrients from the foods that is consumed. The condition is also more prevalent in people with small intestine that has been significantly damaged. The condition can be classified as mild, moderate, or severe, depending on the capability of the small intestine to keep functioning. Parenteral support is a widely used treatment options for patients with short bowel syndrome. In parenteral support, patients receive intravenous nutrients, hydration or electrolytes instead of by mouth.   The physiologic course of short bowel syndrome is divided into the following phases: acute phase and adaptation phase. In acute phase, high intestinal fluid loss and the metabolic derangement is observed. In adaptation phase, structural and functional changes are observed in remaining small bowel an